The Substance
Overview
A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
Where to Watch
Hulu
Subscription
HBO Max Amazon Channel
Subscription
MUBI
Subscription
MUBI Amazon Channel
SubscriptionCast
Demi Moore
Elisabeth
Margaret Qualley
Sue
Dennis Quaid
Harvey
Edward Hamilton-Clark
Fred
Gore Abrams
Oliver
Oscar Lesage
Troy
Christian Erickson
Man at Diner
Robin Greer
Male Nurse
Tom Morton
Doctor
Hugo Diego Garcia
Diego - Boyfriend
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▶Frequently Asked Questions about The Substance
Where can I watch The Substance?
You can watch The Substance on Hulu, HBO Max Amazon Channel, MUBI, MUBI Amazon Channel.
Can I rent The Substance online?
Yes, you can rent The Substance online from the following services: Amazon Video, Apple TV Store, Fandango At Home.
Can I buy The Substance digitally?
Yes, you can buy The Substance digitally from: Amazon Video, Apple TV Store, Fandango At Home.
Is The Substance in theaters?
The Substance is not currently playing in theaters. It has either finished its theatrical run or was released exclusively for digital platforms.